Successful treatment of refractory erosive lichen planus with abrocitinib: A case report

Erosive lichen planus is a rare, chronic, immune-mediated inflammatory disease that can lead to significant morbidity. Erosive lichen planus is often resistant to therapies, and spontaneous remission is uncommon. We report the case of a 62-year-old woman with severe and refractory erosive lichen planus involving the oral, genital, and esophageal mucosa, who failed multiple systemic treatments. Initiation of abrocitinib, a selective Janus Kinase 1 inhibitor, led to complete and sustained clinical remission.