Related Experiment Video
Updated: May 11, 2026

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
Published on: August 26, 2021
Severe Hyperkalemia With Cardiac Conduction Abnormalities in a 92-Year-Old Woman: First Reported Case in Illinois,
Victor O Adedara1, Samer Kholoki2, Keenan Kassar3
1Medicine, St. George's University School of Medicine, West Indies, GRD.
Abstract:
Hyperkalemia, defined as a serum potassium level greater than 5.0 mEq/L, disrupts electrolyte balance and may cause neuromuscular symptoms, including palpitations, fatigue, or weakness. Severe cases exceeding 6.5 mEq/L can lead to life-threatening arrhythmias and cardiac arrest if left untreated. We present a 92-year-old female with stage 4 chronic kidney disease, diastolic heart failure, and a chronic right leg ulcer who arrived at the emergency department with lethargy and intermittent confusion following a fall. Laboratory results revealed a potassium level of 9.7 mEq/L, an estimated creatinine clearance of 9.4 mL/minute, a renal function index of 10.5, a bicarbonate level of 10.9 mEq/L, and a pH of 7.19. ECG demonstrated sinus bradycardia at 40 bpm, low-amplitude P waves, mild PR prolongation, and tall, narrow, symmetric T waves, most prominent in V2-V3 and multiple limb leads. The patient underwent emergent hemodialysis, which normalized her potassium level to 4.3 mEq/L within 24 hours. A repeat ECG showed resolution of abnormalities and restoration of a sinus rhythm at 95 bpm. This case highlights the life-saving importance of rapid ECG recognition, immediate laboratory confirmation, and prompt initiation of therapy in the management of severe hyperkalemia.
More Related Videos
10:01High-Throughput Optical Controlling and Recording Calcium Signal in iPSC-Derived Cardiomyocytes for Toxicity Testing and Phenotypic Drug Screening
Published on: March 31, 2022
10:17Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Related Concept Videos
Antiarrhythmic Drugs: Class I Agents as Sodium Channel Blockers
Class 1A Antiarrhythmic Drugs: These drugs work by moderately blocking sodium channels,...
Antiarrhythmic Drugs: Class III Agents as Potassium Channel Blockers
Heart Failure Drugs: Inotropic Agents
Dysrhythmias I: Introduction
Dysrhythmias VI: Management of Dysrhythmias
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias