Related Experiment Video
Updated: Jan 9, 2026

Author Spotlight: Advancing Cardiovascular Imaging - Introducing the Spatially Weighted Calcium Score for Early Disease Detection
Published on: September 22, 2023
Computed Tomography Coronary Angiogram as a First-Line Diagnostic Tool in Pregnancy-Associated Spontaneous Coronary
Kiran Sheikh1, Sara Ali1, Divya Gunesh1
1Cardiology, William Harvey Hospital, Kent, GBR.
Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute myocardial infarction, typically affecting younger individuals without traditional risk factors for atherosclerotic cardiovascular disease. The underlying pathophysiology differs entirely from that of atherosclerotic myocardial infarction, necessitating distinct diagnostic and management strategies. When SCAD occurs during pregnancy, it is termed pregnancy-associated SCAD (P-SCAD). Because of its rarity, no standardized guidelines currently exist for the diagnosis and management of P-SCAD. We report the case of a 37-year-old woman at 35 weeks' gestation, with no traditional atherosclerotic risk factors, who presented with chest pain. Her electrocardiogram (ECG) showed subtle changes suggestive of anterior ST-elevation myocardial infarction. Considering the procedural risks associated with an invasive coronary angiogram, a computed tomography (CT) coronary angiogram was performed first, confirming dissection involving the left main stem and proximal left anterior descending (LAD) artery. She experienced a brief episode of pulmonary edema that responded well to furosemide and subsequently remained hemodynamically stable. The patient was monitored in the hospital and later delivered uneventfully about four weeks after the event. This case highlights the value of CT coronary angiogram as a non-invasive diagnostic option in hemodynamically stable antepartum patients with suspected SCAD, providing a safe alternative to invasive angiography in selected cases.
Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute myocardial infarction, typically affecting younger individuals without traditional risk factors for atherosclerotic cardiovascular disease. The underlying pathophysiology differs entirely from that of atherosclerotic myocardial infarction, necessitating distinct diagnostic and management strategies. When SCAD occurs during pregnancy, it is termed pregnancy-associated SCAD (P-SCAD). Because of its rarity, no standardized guidelines currently exist for the diagnosis and management of P-SCAD. We report the case of a 37-year-old woman at 35 weeks' gestation, with no traditional atherosclerotic risk factors, who presented with chest pain. Her electrocardiogram (ECG) showed subtle changes suggestive of anterior ST-elevation myocardial infarction. Considering the procedural risks associated with an invasive coronary angiogram, a computed tomography (CT) coronary angiogram was performed first, confirming dissection involving the left main stem and proximal left anterior descending (LAD) artery. She experienced a brief episode of pulmonary edema that responded well to furosemide and subsequently remained hemodynamically stable. The patient was monitored in the hospital and later delivered uneventfully about four weeks after the event. This case highlights the value of CT coronary angiogram as a non-invasive diagnostic option in hemodynamically stable antepartum patients with suspected SCAD, providing a safe alternative to invasive angiography in selected cases.
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Acute Coronary Syndrome III: Diagnostic Studies
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Coronary Artery Disease V: Interprofessional Care

