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Incidental Hibernoma With an Atypical Presentation: Diagnostic Approach, Pathologic Correlation, and Lessons Learned
Matthew Whalen1, Tina Quach1, David Greenberg2
1Radiology, Saint Louis University School of Medicine, Saint Louis, USA.
Cureus
|December 1, 2025
Summary
Hibernomas, rare brown fat tumors, can mimic liposarcomas on imaging. This case highlights differentiating features of FDG-avid hibernomas, lung hamartomas, and liposarcomas using PET/CT and MRI findings.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Hibernomas are rare, benign tumors of brown adipose tissue.
- They exhibit fluorodeoxyglucose (FDG)-avidity, mimicking malignant lesions on imaging.
- Hibernomas share imaging characteristics with liposarcomas and lipomas, posing diagnostic challenges.

