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Chronic Myeloid Leukemia Harboring a Novel Four-Way Variant Translocation t(7;22;9;15)(p15;q11.2;q34.1;q22) With

Shogo Kamigaki1, Makoto Ito1,2, Satsuki Nakano3,4

  • 1Department of Hematology, Chitahanto Rinku Hospital, Tokoname, JPN.

Cureus
|December 1, 2025
PubMed
Summary

This study details a rare chronic myeloid leukemia case with a novel four-way variant Philadelphia chromosome translocation and double Philadelphia chromosomes. Despite complex genetics, the patient achieved a complete response with dasatinib therapy.

Keywords:
chronic myeloid leukemia (cml)cytogeneticsdasatinibdouble philadelphia chromosomefour-way translocation

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