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Isocitrate Dehydrogenase-Mutant WHO Grade 4 Astrocytoma with BCOR Alteration: Case Report.

Maher Kurdi1, Alaa Alkhotani2, Badr Hafiz3

  • 1Department of Pathology, Faculty of Medicine, King Abdulaziz University, Rabigh, Saudi Arabia.

Case Reports in Oncology
|December 1, 2025
PubMed
Summary

This study reports the first case of a BCOR internal tandem duplication (ITD) in an IDH-mutant WHO grade 4 astrocytoma. This finding expands the known genetic landscape of high-grade astrocytomas.

Keywords:
AstrocytomaBCORHigh gradeIDH1Internal tandem duplication

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