Oxycodone versus sufentanil on pain management for spinal PVP surgery

Area of Science:

• Anesthesiology
• Pain Management
• Spinal Surgery

Background:

• Anesthesia choice is crucial for percutaneous vertebroplasty (PVP), impacting pain relief, sedation, side effects, and patient satisfaction.
• Oxycodone and sufentanil are common analgesics, but their comparative efficacy in PVP pain management is not well-established.

Purpose of the Study:

• To investigate the clinical effectiveness of oxycodone for pain management in spinal percutaneous vertebroplasty (PVP).
• To compare the analgesic effects, sedation levels, adverse reactions, and patient satisfaction between oxycodone and sufentanil in PVP.

Main Methods:

• A retrospective study of 100 patients undergoing spinal PVP, divided into oxycodone (50) and sufentanil (50) groups.
• Anesthesia protocols: Oxycodone group received propofol and oxycodone; Sufentanil group received propofol and sufentanil.
• Comparison of intraoperative parameters, postoperative pain scores (VAS), hemodynamic stability, and adverse events.

Main Results:

• The oxycodone group required less additional propofol and had fewer body movements intraoperatively.
• Postoperative pain scores (VAS) were significantly lower in the oxycodone group at 1 and 3 days after surgery.
• Oxycodone group demonstrated better hemodynamic stability with lower changes in SBP, DBP, HR, and SpO2 postoperatively.

Conclusions:

• Oxycodone hydrochloride is effective for intraoperative pain management in PVP, improving analgesic effects and maintaining hemodynamic stability.
• Oxycodone offers good safety and superior pain relief compared to sufentanil in PVP procedures.
• The findings support the promotion of oxycodone for pain management in percutaneous vertebroplasty.