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Associations Between Chronic Conditions and Physical-Cognitive Performance in Middle-Aged Adults: A Cross-Sectional
1Department of Occupational Therapy, Faculty of Health Sciences, Çankırı Karatekin University, Çankırı, Turkey.
International Journal of Aging & Human Development
|December 1, 2025
Summary
Chronic diseases in middle-aged adults are linked to poorer mobility, balance, and visual memory. However, these differences disappear when adjusting for factors like age and education, emphasizing early assessment needs.
Area of Science:
- Gerontology
- Public Health
- Neurology
Background:
- Chronic noncommunicable diseases are increasing globally, straining healthcare systems, especially in developing nations.
- Middle-aged adults are a critical demographic experiencing the onset of chronic conditions and potential functional decline.
Purpose of the Study:
- To examine the relationship between chronic diseases and functional outcomes (mobility, balance, visual memory) in middle-aged adults.
- To identify key factors influencing mobility in this population.
Main Methods:
- Cross-sectional study of 97 participants aged 40-64, categorized by the Age-Adjusted Charlson Comorbidity Index.
- Assessed mobility (Timed Up and Go Test), static balance (One-Leg Standing Test), dynamic balance (Y Balance Test), and visual memory (Rey-Osterrieth Complex Figure Test).
Main Results:
- Initially, individuals with chronic diseases showed significantly lower scores in mobility, balance, and visual memory (P < .05).
- After adjusting for age, BMI, education, and employment, these group differences were not statistically significant.
- Mobility was significantly associated with age, education, static balance, and right foot dynamic balance.
Conclusions:
- While initial findings suggest chronic diseases impact function, confounding factors mask direct associations in middle-aged adults.
- Mobility is influenced by age, education, and balance capabilities.
- Early assessment and preventive interventions for mobility, balance, and cognitive function are crucial for middle-aged individuals with chronic diseases.
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