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High-Resolution 3-Dimensional MRI of the Oculomotor Nerve: Anatomic and Pathologic Considerations by Segment
Marinos Kontzialis1, Max Sheng, Shruti Kumari
1Division of Neuroradiology (MK), Department of Radiology, Northwestern Memorial Hospital, Chicago, Illinois; Division of Neuroradiology (MS, SK, MLM, ORE, ENS, WOM, DAH, AMB), Department of Radiology, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, Ohio; Division of Neuro-Ophthalmology (MLM), Department of Neurology, University Hospitals, Case Western Reserve University School of Medicine, Cleveland, Ohio; Department of Neurosurgery (PT), Northwestern Memorial Hospital, Chicago, Illinois; and Department of Interventional Radiology (DX), Memorial Sloan Kettering Cancer Center, Manhattan, New York.
Background:
CN III is a pure motor cranial nerve that innervates the majority of the extraocular muscles. CN III palsy is the most common cranial nerve palsy with an incidence of 3-4 cases per 100,000.
Evidence Acquisition:
High-resolution, 3-dimensional, skull base MRI allows for high spatial resolution and high signal-to-noise ratio allowing for optimal evaluation of CN III pathology by segment.
Results:
A systemic approach is used to describe the segmental anatomy of CN III, its vascular supply, clinical pathologic manifestations, and imaging correlate.
Conclusions:
We present a segmental approach to high-resolution 3-dimensional MRI of the oculomotor nerve from nuclear to extraforaminal segments.
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