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Updated: May 3, 2026

Alternating Magnetic Field-Responsive Hybrid Gelatin Microgels for Controlled Drug Release
Published on: February 13, 2016
Mild preheating-induced myosin supramolecular hydrogels: A thermoresponsive food material with reversibility and
Li Hu1, Shuyi Song1, Ruibang Zhang1
1College of Food Science, Shenyang Agricultural University, Shenyang 110000, China.
Abstract:
The thermo-responsive properties of myosin provide a theoretical basis for personalized design of myosin-based hydrogels. In this study, myosin supramolecular hydrogels (MSHs) dominated by non-covalent bonds were prepared via the synergistic regulation of ionic strengths (0.3-0.6 M NaCl) and preheating temperatures (45-50 °C). Specifically, MSHs exhibited excellent reversibility: for those with 0.5 and 0.6 M NaCl, the thixotropic recovery ratio exceeded 60 %, and their viscoelasticity was completely restored after secondary thermal treatment. By contrast, with the involvement of covalent bonds, the strain response evolved from a smooth, flexible transition to an abrupt, rigid shift. Notably, at a protein concentration of 50 mg/mL, MSHs with excellent self-supporting, water-holding, and plasticity were obtained. Owing to the superior plastic deformability under pressure and shear forces, MSHs with self-supporting properties can serve as edible ink for high-precision 3D printing. Our findings provide a potential solution to the personalized applications of myosin-based hydrogels.
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