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MultiModal craniocerebral diagnose based on 3D CT and image reports
Wenxuan He1, Qishen Chen1, Wei Gao2
1Shanghai University, Shanghai, 200444, China.
Scientific Reports
|December 1, 2025
Summary
This study introduces a multimodal cranial diagnosis model (MM-CD) that combines 3D CT scans and imaging reports. The MM-CD model enhances diagnostic accuracy for brain lesions, improving patient care during emergencies.
Area of Science:
- Medical imaging analysis
- Artificial intelligence in healthcare
- Radiology and diagnostic imaging
Background:
- Current cranial CT diagnostic methods often use single-modal data, leading to information loss or insufficient characterization.
- Reliance on single CT slices misses cross-slice lesion information, while reports lack pixel-level detail.
- 3D Convolutional Neural Networks (CNNs) struggle with identifying very small lesions in full 3D scans.
Purpose of the Study:
- To develop a multimodal diagnostic model (MM-CD) integrating 3D CT findings and imaging reports for improved cranial lesion diagnosis.
- To address limitations of single-modal approaches and enhance the characterization of small, sparse lesions.
- To reduce missed-diagnosis rates and shorten treatment times in acute care settings.
Main Methods:
- A novel multimodal diagnostic model (MM-CD) was developed, integrating 3D CT scans and textual imaging reports.
- Utilized a 2D pretrained model with a vertical-dimension weight generation module to focus on abnormal CT slices.
- Implemented a multi-scale image fusion module to consolidate lesion information across slices.
- Incorporated a self-attention mechanism to integrate CT data with imaging reports for a comprehensive diagnostic reference.
Main Results:
- The MM-CD model demonstrated improved diagnostic accuracy by integrating multimodal data.
- Achieved a 1.65% increase in overall accuracy compared to existing state-of-the-art multimodal models on a clinical dataset.
- Successfully consolidated lesion descriptions from multiple CT slices and enhanced characterization.
Conclusions:
- The proposed MM-CD model effectively leverages multimodal data for cranial lesion diagnosis.
- This approach shows significant potential in reducing missed diagnoses of small lesions and improving efficiency in acute care.
- Multimodal integration offers a promising direction for advancing AI-driven diagnostic tools in medical imaging.
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