Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Lipids as Anchors

Lipids as Anchors

In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular interactions, solubility, and cytotoxic activity of 4‑hydroxycoumarin in choline chloride‑based acidic deep eutectic solvents.

Scientific reports·2026

Same author

Effects of some surface active ionic liquids on the aqueous solubility, thermodynamic properties and fluorescence behavior of drug diclofenac sodium.

Scientific reports·2026

Same author

Enhancement of SiO<sub>2</sub> based nanofluid stability and thermophysical properties using surface active ionic liquids.

Discover nano·2026

Same author

Industrial extraction of lithium from Urmia Lake using precipitation and evaporation methods.

Scientific reports·2026

Same author

Correction: The effect of protic ionic liquid in the reduction of air contaminant gases emitted from electrical discharge machining in the presence of magnetic field.

Scientific reports·2025

Same author

The surface and micellar properties of ethanolamine based surface active ionic liquids in the presence of drug aspirin.

Scientific reports·2025

Search research articles

Related Experiment Video

Updated: Jul 12, 2026

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

Microencapsulation of curcumin using a fatty acid-based eutectic mixture.

Fariba Ghaffari¹, Hemayat Shekaari²

¹Department of Physical Chemistry, University of Tabriz, Tabriz, Iran.

Scientific Reports

|December 1, 2025

Summary

This study microencapsulated curcumin, a natural compound, within a bio-based phase change material (PCM). This method enhanced curcumin

Keywords:

Curcumin Drug delivery Eutectic mixture Heat capacity Microencapsulation Phase change material

More Related Videos

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid

Published on: September 20, 2017

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Published on: April 14, 2023

Related Experiment Videos

Last Updated: Jul 12, 2026

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Magnetic and Thermal-sensitive PolyN-isopropylacrylamide-based Microgels for Magnetically Triggered Controlled Release

Published on: July 4, 2017

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid

Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid

Published on: September 20, 2017

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Using Multiple Light Scattering to Examine the Stability of Phyllanthus emblica L. Extracts Obtained with Different Extraction Methods

Published on: April 14, 2023

Area of Science:

Materials Science
Biotechnology
Pharmacology

Background:

Curcumin (CUR) exhibits therapeutic potential but suffers from poor solubility, stability, and bioavailability.
Encapsulation is a key strategy to overcome curcumin's limitations for enhanced therapeutic applications.

Purpose of the Study:

To develop a novel microencapsulation method for curcumin using a bio-based phase change material (PCM).
To characterize the curcumin-loaded PCM microcapsules and evaluate their drug release profile.

Main Methods:

Microencapsulation of curcumin using a eutectic mixture of stearic and lauric acids as a bio-based PCM.
Characterization via FT-IR, SEM, DSC, and TGA.
In vitro release studies in PBS (pH 7.4) at 37°C and 45°C.

Main Results:

Successful microencapsulation of curcumin within the bio-based PCM was confirmed.
Curcumin-loaded microcapsules showed well-defined morphology.
Sustained curcumin release observed, with ~50% and ~60% released at 37°C and 45°C respectively over 24 hours.

Conclusions:

Bio-based PCMs are effective carriers for curcumin microencapsulation and controlled delivery.
This approach holds promise for improving curcumin's therapeutic efficacy in drug delivery systems.