Pituitary tuberculosis in the pediatric population: a systematic review and case report
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.Pediatric pituitary tuberculosis is a diagnostic challenge that mimics pituitary adenoma. Early diagnosis and treatment are crucial to prevent permanent endocrine dysfunction and may require lifelong hormone replacement.
Area Of Science
- Pediatric Endocrinology
- Infectious Diseases
- Neuroscience
Background
- Tuberculosis remains a significant global health issue, even with medical advancements.
- Pituitary tuberculosis, specifically intrasellar tuberculoma, poses diagnostic challenges due to its resemblance to pituitary adenomas.
- Early recognition is vital to prevent long-term complications.
Purpose Of The Study
- To identify and evaluate management strategies for pituitary tuberculosis in children.
- To review existing literature and present a case study on pediatric pituitary tuberculosis.
Main Methods
- A systematic literature review was conducted using PubMed, Cochrane Library, and ScienceDirect.
- Keywords included "pituitary gland," "tuberculosis," "sellar tuberculoma," "children," "pediatric," and "adolescent."
- Publications from 2014-2025 were analyzed, supplemented by a new case presentation.
Main Results
- Eight publications reporting on 8 pediatric cases of sellar/suprasellar tuberculosis were included.
- A total of 9 patients (6 female, 3 male) with a mean age of 10.6 years were analyzed.
- Clinical data, including symptoms, endocrine issues, and imaging findings, were examined.
Conclusions
- Pituitary tuberculosis requires inclusion in the differential diagnosis for sellar masses, despite potential lack of typical clinical or radiological signs.
- A biopsy via a minimally invasive transsphenoidal approach is the gold standard for diagnosis.
- Delayed diagnosis can result in irreversible endocrine dysfunction, necessitating regular monitoring and potential lifelong hormone replacement therapy.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
• Class zero: The individual has no known TB exposure and has a negative tuberculin skin test.
• Class one: The individual has been exposed to...
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...