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A fluorescent probe for sulfur dioxide reveals intracellular reductive stress triggered by natural antioxidants

Sijie Luo1,2, Lie Xiang3, Huihong Liu2

  • 1Guangdong Engineering Technical Research Center for Green Household Chemicals, Guangdong Industry Polytechnic University, Guangzhou, Guangdong, 510300, P. R. China. shileinaoh@163.com.

Chemical Communications (Cambridge, England)
|December 2, 2025
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Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
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