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Interventional therapy for a variant central retinal artery occlusion: A case report
Kunming Xie1, Wei Li1, Qingbo Wang2
1Department of Neurosurgery, Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong, China.
Medicine
|December 2, 2025
Summary
A rare case of central retinal artery occlusion (CRAO) with variant anatomy was successfully treated using microcatheter thrombolysis of the middle meningeal artery, significantly improving vision.
Area of Science:
- Ophthalmology
- Interventional Radiology
- Vascular Medicine
Background:
- Central Retinal Artery Occlusion (CRAO) is a critical condition causing sudden vision loss.
- Variant anatomy of the ophthalmic artery can complicate treatment strategies for CRAO.
- Interventional thrombolysis offers a potential treatment pathway for CRAO.
Purpose of the Study:
- To summarize the clinical experience of interventional thrombolysis for a unique case of CRAO.
- To highlight the successful treatment of CRAO in a patient with variant middle meningeal artery supply.
- To evaluate the efficacy of microcatheter-guided thrombolysis in a specific CRAO variant.
Main Methods:
- A single case of CRAO with unusual vascular anatomy was identified.
- Microcatheter super-selective thrombolysis of the middle meningeal artery was performed.
- Urokinase was administered via microcatheter to dissolve the clot.
Main Results:
- The patient presented with acute, severe vision decline in the left eye.
- The central retinal artery's blood supply originated from a branch of the middle meningeal artery.
- Successful thrombolysis led to significant visual recovery.
Conclusions:
- Transcatheter super-selective thrombolysis of the ophthalmic artery is a viable treatment for CRAO.
- Experience with variant ophthalmic artery anatomy is crucial for improving CRAO patient outcomes.
- This case demonstrates the potential of targeted thrombolysis in complex CRAO cases.
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