Laparoscopic Resection for Ileocecal Intussusception Caused by an Inflammatory Fibroid Polyp: A Case Report

Inflammatory fibroid polyp (IFP) is a rare benign mesenchymal tumor of the gastrointestinal tract, typically found in the stomach, while occurrence in the small intestine is uncommon. Adult ileocecal intussusception caused by an IFP is extremely rare. We report the case of a 56-year-old woman who presented with abdominal pain. Abdominal ultrasonography demonstrated a target sign, and contrast-enhanced computed tomography (CT) revealed ileocecal intussusception with a mesenteric vessel converging sign. Colonoscopy identified a protruding lesion with shallow ulceration in the terminal ileum, and biopsy suggested IFP with marked eosinophilic infiltration, although malignancy could not be excluded. The patient underwent laparoscopic ileocecal resection with D3 lymphadenectomy. Histopathological examination confirmed IFP, showing spindle cell proliferation with abundant eosinophilic infiltration and rich vascularization. Immunohistochemically, the lesion was positive for CD34 and negative for c-kit and DOG1. The postoperative course was uneventful, and the patient was discharged on postoperative day 6. IFP should be considered in the differential diagnosis of adult intussusception in the ileocecal region, and laparoscopic oncologic resection represents an appropriate treatment option when malignancy cannot be ruled out.