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Updated: Aug 8, 2026
Preparation of DNA-crosslinked Polyacrylamide Hydrogels
Published on: August 27, 2014
Cell instructive hydrogels functionalized with polymerized DNA nanostructures
Hee Yeon Kim1, Young Min Kim1, Keonwook Nam1
1Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. yr36@yonsei.ac.kr.
Abstract:
Novel hyaluronic acid hydrogels functionalized with polymerized DNA nanostructures using rolling circle amplification were developed. These hydrogels exhibited enhanced cell attachment and proliferation through functional DNA-mediated interactions. The system maintained favorable physicochemical properties and enhanced interactions with biological interfaces, demonstrating potential for advanced 3D cell culture applications.
