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Published on: June 10, 2025
National Trends and Disparities in Heart Failure Hospitalizations and Inpatient Outcomes Between 2010-2022.
Manyoo A Agarwal1, Shayan Ebrahimian2, Amy Yan3
1Cardio-Oncology Program, Cardiovascular Medicine, Heart Vascular and Thoracic Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, UAE.
Heart failure (HF) hospitalizations rose from 2014 to 2019, then declined, but increased in younger adults (<65 years) while decreasing in older adults (>64 years). In-hospital mortality rose in 2020, reversing prior trends.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Limited data exist on age-standardized heart failure (HF) hospitalization trends.
- Understanding differential rates across demographics is crucial.
Purpose of the Study:
- To assess temporal trends in age-standardized HF hospitalization rates.
- To analyze in-hospital mortality trends for HF patients stratified by age, sex, race, insurance, and location.
Main Methods:
- Analysis of the National Inpatient Sample database (2010-2022).
- Examination of HF hospitalization rates and in-hospital mortality trends across demographic strata.
Main Results:
- Age-standardized HF hospitalizations increased from 2014-2018, then declined.
- Hospitalizations rose in younger adults (<65 years) but fell in older adults (>64 years).
- In-hospital mortality showed no improvement and increased in 2020.
Conclusions:
- HF hospitalizations shifted towards younger populations (<65 years) between 2010-2022.
- A notable increase in in-hospital mortality occurred in 2020.
- Trends varied significantly by age group, insurance, and hospital location.
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