Related Experiment Video
Updated: Jan 9, 2026

Rodent Model of Masseter Volumetric Muscle Loss for Studying Bioengineering Materials
Published on: May 31, 2024
The impact of aging on masseter vestibular evoked myogenic potentials
Anuj Kumar Neupane1, Mugdha Arkadi1
1School of Audiology & Speech-Language Pathology, Bharati Vidyapeeth (Deemed to be University), Pune, India.
Objective:
The present study aims to investigate the impact of advancing age on the response parameters of masseter vestibular evoked myogenic potentials (mVEMP) elicited using various stimulation frequencies.
Design:
mVEMP responses were recorded from participants at six stimulus frequencies-250, 500, 750, 1000, 1500, and 2000 Hz-using tone burst stimuli. Response parameters including P1 and N1 latencies, peak-to-peak amplitude, Inter-Aural Amplitude Ratio (IAAR), and Inter-Frequency Amplitude Ratio (IFAR) were analysed to assess the effects of ageing on mVEMP.
Study Sample:
Sixty participants were divided into three age groups: younger adults (18-35 years), middle-aged adults (36-55 years), and older adults (>55 years).
Result:
A significant prolongation of absolute latencies and a reduction in EMG-scaled peak-to-peak amplitude were observed among participants with increasing age. No significant age-related changes were found on N1 latency or IAAR. IFAR values steadily increased with advancing age.
Conclusion:
The commonly used 500 Hz stimulus may not be optimal for eliciting mVEMP responses in middle-aged and older adults. For improved diagnostic accuracy, frequencies of 750 Hz and/or 1000 Hz should be considered for these age groups.
Related Concept Videos
The Effect of Aging on Tissues
Pharmacodynamics in Geriatric Patients: Effects of Age
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Muscle Stimulation Frequency
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...

