Drivers, barriers, and implications of mpox vaccine uptake in Australia among gay, bisexual, and other men who have sex with men: results from a prospective observational mixed-methods study (2022-2024)
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View abstract on PubMed
Summary
This summary is machine-generated.Australia
Area Of Science
- Epidemiology
- Public Health
- Vaccinology
Background
- Australia experienced a significant mpox resurgence in 2024, primarily affecting males.
- Vaccine coverage among gay, bisexual, and other men who have sex with men (GBMSM) was suboptimal at 50% prior to the outbreak.
- Understanding mpox vaccine uptake drivers and barriers is crucial for effective control strategies.
Purpose Of The Study
- To identify factors influencing mpox vaccine uptake among GBMSM in Australia.
- To explore barriers to vaccination and inform public health interventions.
- To assess vaccine coverage and completion rates in a prospective cohort.
Main Methods
- The TraX study utilized a mixed-method prospective observational design.
- Weekly surveys tracked mpox vaccine uptake in GBMSM and sexual partners.
- Multivariable logistic regression and qualitative analysis of unvaccinated individuals were employed.
Main Results
- High uptake of the first dose (82.8%) and second dose completion (83.7%) were observed.
- Vaccine uptake was associated with factors like living in high-prevalence areas, HIV status, STIs, and mpox concern.
- Barriers included perceived low risk, access issues, limited knowledge, and side effect concerns.
Conclusions
- Despite high initial uptake, Australia's 2024 mpox outbreak indicated insufficient population-level protection.
- Addressing concerns about side effects, streamlining access, and improving risk awareness are key to increasing vaccination rates.
- Enhanced vaccination strategies are needed to prevent future mpox outbreaks.
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