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Updated: May 4, 2026

Heart Dissection in Larval, Juvenile and Adult Zebrafish, Danio rerio
Published on: September 30, 2011
The symphony of shape: A feedback loop conducting zebrafish heart formation
Changchang Cao1, Zheng Li2, Li Wang1
1State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China; Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Hospital Chinese Academy of Medical Sciences-Shenzhen, Shenzhen 518057, China.
None:
Organ structures formed during development dictate their physiological functions. In this issue of Developmental Cell, Andrews et al.1 demonstrate a cellular feedback loop linking trabeculation and compact layer stretching, which depends on actomyosin remodeling mediated by the Notch signaling pathway and orchestrates ventricular morphogenesis in zebrafish.
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