Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Paediatrics
  9. Infant And Child Health
  11. A Rare Coincidence Of Intrarenal Wilms Tumor With Spina Bifida: A Case Report And Review Of The Literature

A rare coincidence of intrarenal Wilms tumor with spina bifida: a case report and review of the literature

Abay Gosaye1, Wassie Almaw Yigzaw1

  • 1Addis Ababa University College of Medicine and Health Sciences Pediatric Surgery Unit, Ethiopia.

International Journal of Surgery Case Reports
|December 3, 2025

Related Experiment Videos

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
04:37

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

1.4K
A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
06:19

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

10.8K
Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

786

View abstract on PubMed

Summary
This summary is machine-generated.

Children with spina bifida have an increased risk of Wilms tumor, a common childhood kidney cancer. This case highlights the importance of investigating flank masses in these patients to detect malignancy early.

Area of Science:

  • Pediatric Oncology
  • Urology
  • Developmental Biology

Background:

  • Children with congenital anomalies face a higher risk of developing childhood malignancies.
  • Nervous system and urinary system anomalies are particularly associated with increased cancer incidence.
  • This report details an intrarenal Wilms tumor case in a patient with spina bifida.

Purpose of the Study:

  • To report a rare case of intrarenal Wilms tumor in an infant with spina bifida.
  • To emphasize the association between congenital anomalies and the risk of Wilms tumor.
  • To highlight the importance of vigilance in diagnosing visceral lesions in patients with spinal dysraphism.

Main Methods:

  • Case presentation of a 4-month-old male with repaired myelomeningocele and flank swelling.
Keywords:
Case reportChildhood malignancyCongenital anomalySpina bifida

Related Experiment Videos

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis
04:37

Unilateral Ureteral Obstruction Model for Investigating Kidney Interstitial Fibrosis

Published on: April 25, 2025

1.4K
A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
06:19

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

10.8K
Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review
04:33

Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

Published on: November 8, 2024

786
  • Diagnostic imaging including abdominopelvic ultrasound and magnetic resonance imaging.
  • Histopathological examination confirming cystic, partially differentiated nephroblastoma (Wilms tumor).

    • Main Results:

    • An intrarenal Wilms tumor (SIOP stage 1, low-risk) was diagnosed.
    • The tumor showed no evidence of lymph node involvement.
    • The patient has remained disease-free during over a year of follow-up.

    Conclusions:

    • Wilms tumor is the most common pediatric renal tumor, often sporadic but linked to chromosomal anomalies.
    • Patients with congenital anomalies like spina bifida have an elevated risk.
    • A high index of suspicion is crucial for diagnosing malignancy in young patients with spinal dysraphism and visceral lesions.
    Wilms tumor