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Updated: Jan 9, 2026

Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays
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[Development of a Laboratory Test for Botulism Using Sandwich ELISA]

Eun-Sun Choi1, So-Hyeon Kim1, Jun-Ho Jeon2

  • 1질병관리청 감염병진단분석국 고위험병원체분석과.

Jugan Geon-Gang Gwa Jilbyeong
|December 3, 2025
PubMed
Summary

New sandwich ELISA kits rapidly detect botulinum toxin A or B. These assays offer high sensitivity and specificity, providing a faster, more reliable alternative to mouse bioassays for diagnosing botulism during outbreaks or bioterrorism events.

Keywords:
Botulinum toxinBotulismMouse bioassaySandwich ELISA

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