Electrocardiographic Manifestations of Hospitalized Adult Patients with Coronavirus Disease 19 (COVID-19): UP-PGH

Felix Eduardo R Punzalan1,2, Paul Anthony O Alad1, Tam Adrian P Aya-Ay1

  • 1Division of Cardiovascular Medicine, Department of Medicine, Philippine General Hospital, University of the Philippines Manila.

Acta Medica Philippina
|December 3, 2025
PubMed

Insights

COVID-19 patients often show normal electrocardiograms (ECG) at baseline, but significant cardiac abnormalities like sinus tachycardia and atrial fibrillation can occur. These ECG changes in COVID-19 patients may indicate underlying cardiac injury.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Medical Diagnostics

Background:

  • COVID-19 (Coronavirus Disease 2019) is linked to cardiac injury.
  • Electrocardiographic (ECG) changes are common indicators of cardiac involvement in COVID-19 patients.

Purpose of the Study:

  • To characterize the cardiovascular and electrocardiographic profiles of adult patients diagnosed with COVID-19.
  • To identify common ECG abnormalities in COVID-19 patients.

Main Methods:

  • Retrospective analysis of 998 adult COVID-19 patients from June 2021 to June 2022.
  • Review of clinical profiles and 12-lead ECG tracings from electronic medical records.
  • Independent review of ECGs by three cardiologists with descriptive analysis.

Main Results:

  • Most common comorbidities: hypertension, diabetes, dyslipidemia.
  • Significant ECG abnormalities included sinus tachycardia (22.8%) and atrial fibrillation (11.02%).
  • Ischemic findings: ST depression (2.91%), T-wave inversion (1.70%), ST elevation (2.71%).

Conclusions:

  • Baseline ECGs in COVID-19 patients are often normal but can reveal significant abnormalities.
  • Sinus tachycardia, atrial fibrillation, and ischemic changes are frequent ECG findings.
  • These ECG abnormalities in COVID-19 patients warrant clinical attention due to potential cardiac implications.
Abstract

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