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What Does the PCL-5 Measure? A Conjoint Hierarchical Analysis Using the MMPI-3.

William H Menton1, Paul A Arbisi1,2, Melissa A Polusny1,2,3

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|December 3, 2025
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This summary is machine-generated.

The PTSD Checklist for DSM-5 (PCL-5) may measure general distress, not just PTSD symptoms. Conjoint analysis with the MMPI-3 revealed distinct symptom clusters, offering more specific insights into posttraumatic stress disorder.

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Area of Science:

  • Psychology
  • Psychiatry
  • Clinical Assessment

Background:

  • The PTSD Checklist for DSM-5 (PCL-5) is a common tool for screening posttraumatic stress disorder (PTSD) symptoms.
  • Debate exists regarding whether the PCL-5 measures PTSD-specific symptoms or broader psychological distress.
  • The Minnesota Multiphasic Personality Inventory-3 (MMPI-3) is a comprehensive assessment for psychological difficulties.

Purpose of the Study:

  • To clarify the underlying factors measured by the PCL-5.
  • To examine the relationship between PCL-5 items and MMPI-3 scales in a veteran sample.
  • To differentiate PTSD-specific symptoms from general distress using conjoint factor analysis.

Main Methods:

  • Conjoint exploratory factor analyses were performed on PCL-5 items and MMPI-3 scales.
  • A sample of 386 United States veterans and their partners was utilized.
  • Statistical analyses examined the factor structure and cross-loadings between the two instruments.

Main Results:

  • PCL-5 items were explained by three factors: affect/cognitions, traumatic intrusion/avoidance, and hyperarousal.
  • The affect/cognition factor on the PCL-5 was associated with general demoralization/distress from the MMPI-3.
  • The hyperarousal factor cross-loaded with MMPI-3 somatic and cognitive scales, while intrusions/avoidance showed minimal overlap.

Conclusions:

  • The PCL-5 may capture transdiagnostic factors like demoralization alongside PTSD symptoms.
  • Analyzing individual PCL-5 symptom clusters can provide more specific insights into posttraumatic symptomatology.
  • Findings support a multidimensional view of PTSD assessment and treatment.