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Updated: Jan 9, 2026

Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling
Published on: November 17, 2019
COCOMAPS 2.0: a web server for identifying, analyzing, and visualizing atomic interactions at the interface of
Mohit Chawla1, Utkarsh Kalra1, Andrea Petta2
1Physical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia.
Summary:
Herein, we present COCOMAPS 2.0, for the analysis, visualization, and comparison of the interface in protein-protein and protein-nucleic acid complexes. COCOMAPS 2.0 complements the residue-level and buried surface area analyses of the original COCOMAPS tool with a comprehensive and accurate atomic-level characterization of the interface, enabling detailed interpretation of molecular recognition. Furthermore, it provides a greatly enhanced flexibility, interactivity, and efficiency in graphical visualizations.
Availability And Implementation:
COCOMAPS 2.0 is accessible as a public web tool at https://aocdweb.com/BioTools/cocomaps2 and as a standalone code at https://doi.org/10.5281/zenodo.17390665.
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