Enhanced resolution real-time electrical heart models

Real-time electrical heart models show promise for interacting in closed loop with medical devices to assist design and verification. A heart model based on hybrid automata formalism on a graph/network is progressively expanded to ascertain predicted activation sequence, performance and thresholds for real-time functionality. Software solutions are found using Matlab® Simulink® and initial steps are made toward hardware in the loop testing on the Speedgoat® platform. In software the heart model remains real-time with up to 644 nodes and 2802 edges. Enhanced resolution while retaining real-time performance enables capturing disease features such as myocardial infarct and the resulting altered sequences of electrical activity.Clinical Relevance- This heart model with real time interaction capacity can be used for parameter setting training and medical device design and verification.