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iEMG-Based Diagnosis of ALS and Myopathy using 1D-CNN

Sidi Mohamed Sid'El Moctar, Chawki Nasrallah, Imad Rida

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 3, 2025
    PubMed

    Abstract:

    Amyotrophic Lateral Sclerosis (ALS) and myopathy are debilitating neuromuscular disorders that require accurate and timely diagnosis for effective management. Traditional electromyography (EMG)-based diagnostic methods rely on manual interpretation, which is time-consuming and prone to variability. This study proposes an approach that directly classifies EMG signals using a one-dimensional convolutional neural network (1D-CNN) without feature extraction, addressing the limitations of existing methods that depend on handcrafted features and focus primarily on binary classification. The proposed model is evaluated on a publicly available EMG dataset, achieving an overall accuracy of 99.27%, with macro and weighted precision, recall, and F1-scores exceeding 99% across ALS, myopathy, and healthy subjects. Unlike previous approaches that require extensive preprocessing, our method maintains high classification performance while reducing computational complexity, offering a clinically relevant multiclass classification framework. Although our method achieves high classification performance, it also maintains a strong balance between sensitivity and specificity, ensuring reliable and accurate neuromuscular disorder diagnosis, making it a practical tool for clinical applications. Future research will focus on improving model generalizability, expanding dataset diversity, and integrating real-time deployment for enhanced diagnostic utility.

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