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Related Concept Videos

Nociception01:44

Nociception

28.4K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
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Related Experiment Video

Updated: May 6, 2026

Electrophysiological Measurements and Analysis of Nociception in Human Infants
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Electrophysiological Measurements and Analysis of Nociception in Human Infants

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ScorER: Exploring Annotation Bias in Vision-Based Neonatal Pain Assessment.

Yuxin Ni, Huaiyu Zhu, Yisheng Zhao

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 3, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Neonatal pain assessment tools can be improved by ScorER, a new AI system that identifies and corrects errors in vision-based pain annotations. This helps create better AI for managing infant pain.

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    Area of Science:

    • Medical Informatics
    • Artificial Intelligence
    • Neonatal Medicine

    Background:

    • Neonatal pain negatively impacts brain development, necessitating accurate pain assessment.
    • Automated pain assessment systems are crucial but face data collection and annotation challenges.
    • Vision-based annotation is prone to real-world disturbances, leading to data errors.

    Purpose of the Study:

    • To introduce Scoring Error Recognition (ScorER), a deep neural network tool for identifying vision-based annotation bias in neonatal pain assessment.
    • To enhance the quality and reliability of data used for developing automated neonatal pain assessment systems.

    Main Methods:

    • Developed a deep neural network-based tool, ScorER.
    • Integrated the Grad-CAM algorithm to identify key regions linked to annotation bias.
    • Utilized a data-driven approach to analyze the causes of annotation errors.

    Main Results:

    • ScorER effectively identifies and diagnoses biases in vision-based neonatal pain annotations.
    • The Grad-CAM integration pinpoints regions contributing to annotation inaccuracies.
    • The study provides a method to improve annotation quality for AI development.

    Conclusions:

    • ScorER assists caregivers in producing high-quality annotations for neonatal pain.
    • This tool supports the creation of large-scale, reliable clinical databases for AI applications.
    • Facilitates advancements in AI-driven automated neonatal pain assessment and management.