Related Experiment Video
Updated: Jan 9, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Titration and Treatment of Virtual Type 2 Diabetes Patients using an Adaptive Automated Insulin Delivery System
None:
We test a fully automated insulin delivery (AID) system designed for patients with type 2 diabetes (T2D). Initially, the system uses an integral (I) controller to titrate the basal insulin rate, followed by the introduction of a proportional-derivative (PD) controller for managing post-prandial glucose levels. The system is adaptive and intended to be applicable to any patient without prior calibration. We employ an augmented integrated glucose insulin (IGI) model to simulate 278 virtual patients for a virtual trial of the proposed system. These trials demonstrate that the AID system safely and effectively titrates and manages insulin without need for meal announcements, highlighting its potential for providing safe and convenient insulin management in T2D.
More Related Videos
06:32Author Spotlight: Automated Deep Brain Stimulation for Parkinson's Disease - Exploring the Possibilities and Challenges of Home Monitoring
Published on: July 14, 2023
08:32Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain
Published on: January 4, 2018
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational
Dosage Regimen: Individualization