Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Fields01:27

Magnetic Fields

7.1K
A moving charge or a current creates a magnetic field in the surrounding space, in addition to its electric field. The magnetic field exerts a force on any other moving charge or current that is present in the field. Like an electric field, the magnetic field is also a vector field. At any position, the direction of the magnetic field is defined as the direction in which the north pole of a compass needle points.
A magnetic field is defined by the force that a charged particle experiences...
7.1K
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

1.1K
The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
1.1K
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.9K
Atomic Nuclei: Nuclear Relaxation Processes01:23

Atomic Nuclei: Nuclear Relaxation Processes

1.2K
In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis.
1.2K
NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences01:17

NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences

1.7K
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
1.7K
Atomic Nuclei: Nuclear Magnetic Moment00:59

Atomic Nuclei: Nuclear Magnetic Moment

3.1K
All atomic nuclei are positively charged. When they have a nonzero spin, they behave like rotating charges. As a consequence of their charge and spin, these nuclei generate a magnetic field (B). This, in turn, gives rise to a magnetic moment (μ), which is randomly oriented in the absence of an external magnetic field. When an external magnetic field (B0) is applied, the magnetic moment vectors can align with the field or against it in 2 + 1 orientations. A hydrogen nucleus, which is just a...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A scalable synthesis of N-doped Si nanoparticles for high-performance Li-ion batteries.

Chemical communications (Cambridge, England)·2016
Same author

The effect and action mechanism of resveratrol on the vascular endothelial cell by high glucose treatment.

Saudi journal of biological sciences·2016
Same author

Altered resting state functional connectivity of anterior insula in young smokers.

Brain imaging and behavior·2016
Same author

Curdlan blocks the immune suppression by myeloid-derived suppressor cells and reduces tumor burden.

Immunologic research·2016
Same author

Combined image guided monitoring the pharmacokinetics of rapamycin loaded human serum albumin nanoparticles with a split luciferase reporter.

Nanoscale·2016
Same author

Distinctive effects of CD34- and CD133-specific antibody-coated stents on re-endothelialization and in-stent restenosis at the early phase of vascular injury.

Regenerative biomaterials·2016

Related Experiment Video

Updated: Jan 9, 2026

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.9K

Single-Sided Magnetic Particle Imaging Based on Magnetic Field Rotation Encoding.

Yang Jing, Siao Lei, Pengyu Huang

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 3, 2025
    PubMed
    Summary

    This study introduces a new Magnetic Particle Imaging (MPI) method using Magnetic Particle Spectroscopy (MPS) to improve imaging depth and sensitivity. This advancement enhances diagnostic capabilities for conditions like cancer.

    More Related Videos

    Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
    07:42

    Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

    Published on: July 20, 2022

    3.2K
    Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement
    09:43

    Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement

    Published on: November 7, 2017

    9.8K

    Related Experiment Videos

    Last Updated: Jan 9, 2026

    Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
    07:01

    Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

    Published on: June 9, 2016

    9.9K
    Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains
    07:42

    Optimizing Magnetic Force Microscopy Resolution and Sensitivity to Visualize Nanoscale Magnetic Domains

    Published on: July 20, 2022

    3.2K
    Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement
    09:43

    Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement

    Published on: November 7, 2017

    9.8K

    Area of Science:

    • Medical Imaging
    • Biomedical Engineering
    • Nanotechnology

    Background:

    • Magnetic Particle Imaging (MPI) is a promising nonionizing, high-resolution medical imaging technique.
    • Current MPI systems, particularly single-sided devices, suffer from limited imaging depth and sensitivity, hindering clinical use.
    • Applications include vascular imaging, cell tracking, inflammation imaging, and cancer diagnosis.

    Purpose of the Study:

    • To develop a novel encoding method for MPI to overcome limitations in imaging depth and sensitivity.
    • To enhance the clinical applicability of MPI, especially for early cancer detection.

    Main Methods:

    • Proposed a new encoding method leveraging high-sensitivity Magnetic Particle Spectroscopy (MPS) systems.
    • Conducted theoretical analysis and simulation experiments to validate the approach.

    Main Results:

    • The novel method demonstrated enhanced imaging depth compared to conventional single-sided MPI devices.
    • Significant improvements in sensitivity were observed.
    • Preliminary findings suggest potential for cost-effectiveness and reduced equipment complexity.

    Conclusions:

    • The proposed MPS-based encoding method offers a promising solution to improve MPI performance.
    • This advancement could significantly boost the clinical utility of MPI for early diagnosis of critical conditions like cancer.