Development of a Biliary Biofluid Dynamics Measurement Platform Utilizing Particle Image Velocimetry (PIV)

Biliary systems are one of the most crucial organs in human physiology, perforating bile secretion and transport. Due to its complex physiological and anatomical structure, the biliary system operates through highly intricate mechanisms involving fluid dynamics, biochemistry. The aim of this research is to develop a biliary biofluid dynamics measurement platform based on Particle Image Velocimetry (PIV) methods for the characterization of fluid mechanical properties of the biliary system. The experimental platform consisting of the PIV unit, the experimental unit, and a high-performance computing unit, is capable to simulate several patho-physiological conditions within the biliary tract and thus provide flow field information in the model. By introducing tracer particles into a biliary fluid, PIV technique is utilized to capture and analyze the motion trajectories of these particles, reconstructing the complex flow patterns within the biliary tract and providing key data for the study of related diseases. This platform is expected to offer new insights and potential utilities for research efforts in biliary fluid dynamics.