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High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
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Learned k-space Partitioning for Optimized Self-Supervised MRI Reconstruction

Brenden Kadota, Charles Millard, Mark Chiew

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 3, 2025
    PubMed

    Abstract:

    Self-supervised magnetic resonance imaging (MRI) reconstruction methods train deep learning networks without the need for fully sampled reference data. One such approach, self-supervised via data under-sampling (SSDU), partitions under-sampled k-space into two disjoint sets, with a neural network mapping between them. However, SSDU and its variants rely on heuristic k-space partitioning, which may lead to suboptimal performance and necessitates new partitioning schemes when initial under-sampling patterns change. In this work, we propose a novel approach to learn optimal k-space partitioning by modeling a probability distribution which we use for partitioning. Specifically, we employ the LOUPE framework to learn an optimal partitioning probability distribution. Furthermore, we introduce a weighted dual-domain self-supervised loss function that incorporates both k-space and image-space loss terms. Evaluations on the fastMRI dataset demonstrate that our dual-domain learned partitioning method outperforms existing partitioning strategies and adapts to new sampling patterns without requiring hand-picked partitioning methods.Clinical Relevance- Typical clinical MRI protocols are under-sampled and reconstructed using parallel imaging. Self-supervised reconstruction can train directly on under-sampled clinical data, eliminating the need for separately acquired fully sampled datasets.

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