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    Summary
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    This study introduces a novel fine-tuning method for Large Language Models (LLMs) to detect depression with high accuracy and low memory usage. The approach surpasses prompt-engineered models, offering a more efficient solution for mental health analysis.

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    Area of Science:

    • Artificial Intelligence
    • Computational Psychiatry
    • Natural Language Processing

    Background:

    • Depression significantly impacts society, necessitating early detection for effective treatment.
    • Large Language Models (LLMs) show promise in depression detection, with prompt-engineering outperforming fine-tuning in recent studies.
    • Fine-tuning LLMs for depression detection traditionally requires substantial memory, limiting accessibility.

    Purpose of the Study:

    • To develop a fine-tuning method for LLMs that achieves higher accuracy than prompt-engineered models for depression detection.
    • To minimize GPU memory requirements during the LLM training process.
    • To validate the model's performance on both public and private datasets.

    Main Methods:

    • Quantized the parameters of the LLM to reduce memory footprint during training.
    • Retained the original LLM structure, training it as a generative model without adding a classification layer.
    • Evaluated the model on the DAIC-WOZ and a private PROMPT dataset for depression detection.

    Main Results:

    • Achieved an F1 score of 84% for depression detection on the DAIC-WOZ dataset using low GPU memory.
    • Demonstrated superior performance compared to prompt-engineered models.
    • Attained an F1 score of 82% on the private PROMPT dataset, indicating robustness beyond pre-training data.

    Conclusions:

    • The proposed fine-tuning method effectively detects depression with high accuracy and low memory requirements.
    • This approach offers a more memory-efficient alternative to prompt-engineering for LLM-based depression detection.
    • The model's strong performance on a private dataset suggests generalizability and reduced reliance on publicly available pre-training data.