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A Machine Learning Framework for Efficient Triage of Long-COVID Patients to Specialists

Argyrios Kerezis, Archontoula Antonoglou, Andreas Asimakos

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
    |December 3, 2025
    PubMed

    Abstract:

    Long-COVID poses a significant burden on healthcare systems, necessitating efficient triaging strategies to optimise patient care. This study presents a machine learning (ML) framework for prioritising long-COVID patients for specialist consultations in cardiology, pulmonology, and psychiatry. Utilising a dataset of 175 patients, a Support Vector Machine model was developed, and subsequently enhanced with Synthetic Minority Oversampling Technique for class imbalance handling. The model yielded an accuracy of 0.67 and an Area-Under-the-Curve of 0.84, outperforming alternative models such as Random Forest, k-nearest neighbours, XGBoost, and Decision Trees. Notably, the SF-36 General Health score emerged as the most critical factor in patient classification, followed by bodily pain and anxiety levels. These findings demonstrate the potential of ML-based approaches to streamline healthcare resource allocation and improve patient outcomes. Future work will assess the clinical impact of this approach in prospective studies.Clinical Relevance- This study proposes a machine-learning-driven method to enhance specialist triaging for long-COVID patients, offering potential for improved healthcare resource allocation and timely patient care.

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