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Updated: Jan 9, 2026

Lateral Root Inducible System in Arabidopsis and Maize
Published on: January 14, 2016
OsNBR1 promotes lateral root development through the degradation of OsIAA11
Wanying Sun1, Junling Wang1, Bing Xu1
1College of Life Science, Hebei Normal University, Shijiazhuang, China.
Abstract:
In eukaryotes, unnecessary/damaged proteins are mainly degraded through the ubiquitin-26S proteasome system (UPS) and/or the autophagy pathway. Lateral roots (LR) play a vital role in the absorption of water and nutrients as well as in responding to multiple environmental stimuli. Aux/IAAs regulate the auxin signaling pathway negatively and play pivotal roles in regulating root development. In this study, OsNBR1, an autophagy cargo receptor in rice, was extensively characterized. OsNBR1 could link the UPS and the autophagy pathway through the OsUBI3-OsNBR1-OsATG8s module, as well as the interaction with OsRPT1/OsRPN10 (the proteasome subunits). OsNBR1 is more abundant in the steles in the root mature zone and the LRs. The expression of OsNBR1 could be affected by treatments with IAA, NAA, and NPA. Functionally, OsNBR1 contributes to promoting the LR development and IAA accumulation. Moreover, OsNBR1 interacts with OsIAA11 (a negative regulator of LR formation) physically and promotes its degradation through the UPS and the autophagy pathway. In addition, OsNBR1 functions upstream of OsIAA11. This study provided new insights into the function of OsNBR1 in regulating the LR formation by identifying its autophagic cargo OsIAA11, which broadly expanded our knowledge of the mechanisms of NBR1s in controlling plant development.
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