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Updated: Jan 9, 2026
06:55
Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
Published on: February 14, 2022
2.1K
Pleural space complications after lung transplantation.
Mark Shacker1, Lucas Wang1, Lucia Chang1
1Creighton University School of Medicine, Phoenix, Ariz.
The Journal of Thoracic and Cardiovascular Surgery
|December 3, 2025
Summary
Lung transplant patients needing intervention for pleural space issues had worse survival. However, surgical and non-surgical treatments yielded similar outcomes for these lung transplant complications.
Area of Science:
- Thoracic Surgery
- Transplant Surgery
- Pulmonary Medicine
Background:
- Pleural space complications are frequent following lung transplantation.
- These complications can significantly impact patient outcomes.
Purpose of the Study:
- To compare outcomes between lung transplant recipients who underwent posttransplant pleural space surgery and those who did not.
- To evaluate the effectiveness of surgical versus non-surgical interventions for pleural space complications after lung transplantation.
Main Methods:
- Retrospective review of 840 primary bilateral lung transplant recipients.
- Propensity matching was used to compare 96 patients undergoing pleural space surgery with 192 patients receiving only non-surgical intervention.
Main Results:
- Patients requiring any intervention (surgical or non-surgical) for pleural space complications had reduced median survival (4.99 years) compared to those without intervention (5.70 years).
- Survival rates at 1, 3, and 5 years post-transplant were comparable between the surgical and non-surgical intervention groups.
- Early surgery (within 90 days) and fewer prior non-surgical interventions showed a trend toward improved survival.
Conclusions:
- Lung transplant recipients with pleural space complications requiring intervention face poorer outcomes.
- Surgical intervention for pleural space complications after lung transplantation demonstrated comparable outcomes to non-surgical management.
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