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5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
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Challenging laparoscopic radical nephrectomy in pregnancy.

Matthew Kwon1, Ahmad Alam2, Eugene Mansour3

  • 1Urology, Hunter New England Local Health District, New Lambton, New South Wales, Australia mkwon98@hotmail.com.

BMJ Case Reports
|December 3, 2025
PubMed
Summary

Managing renal cell carcinoma (RCC) in pregnancy requires balancing cancer treatment with fetal safety. Laparoscopic nephrectomy during the second trimester proved successful for a large clear cell RCC, ensuring good outcomes for mother and baby.

Keywords:
AnaesthesiaCancer - see OncologySurgical Procedure, OperativeUrological cancerUrology

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Area of Science:

  • Oncology
  • Obstetrics
  • Surgical Innovation

Background:

  • Renal cell carcinoma (RCC) during pregnancy is exceptionally rare.
  • It poses significant challenges in balancing maternal cancer treatment with fetal well-being.
  • Clinical decisions require careful consideration of oncological urgency versus obstetric risks.

Purpose of the Study:

  • To present a successful management strategy for a pregnant patient with clear cell renal cell carcinoma.
  • To highlight the feasibility and safety of surgical intervention during pregnancy.
  • To emphasize the importance of a multidisciplinary approach in complex cases.

Main Methods:

  • Case report of a pregnant patient with an incidentally detected large clear cell RCC.
  • Surgical management involved laparoscopic radical nephrectomy.
  • Intervention was performed during the second trimester of pregnancy.

Main Results:

  • Successful surgical removal of the renal cell carcinoma.
  • Favorable oncological and fetal outcomes were achieved.
  • The patient and fetus tolerated the procedure well.

Conclusions:

  • Laparoscopic radical nephrectomy is a viable and safe option for managing renal cell carcinoma in pregnant patients.
  • Multidisciplinary collaboration is crucial for optimizing outcomes.
  • Tailored surgical planning is essential for achieving success in these unique cases.