Related Experiment Video
Updated: Jan 9, 2026
11:02
Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
Published on: November 29, 2024
1.0K
[Progress in metabolomics of multiple myeloma]
1Department of Hematology, the First Affiliated Hospital with Nanjing Medical University, Jiangsu Province Hospital, Nanjing 210029, China.
Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi
|December 3, 2025
Summary
Multiple myeloma (MM) involves metabolic reprogramming, where abnormal metabolism fuels cancer cell growth and resistance. Metabolomics aids in identifying biomarkers and therapeutic targets for improved MM diagnosis and treatment.
Area of Science:
- Biochemistry
- Oncology
- Metabolomics
Background:
- Multiple myeloma (MM) is a cancer of plasma cells characterized by significant metabolic reprogramming.
- Aberrant metabolism of amino acids, glucose, lipids, and nucleotides is integral to MM pathogenesis, influencing proliferation, metastasis, immune evasion, and drug resistance.
Purpose of the Study:
- To review the application of metabolomics in identifying multiple myeloma biomarkers.
- To explore the targeting of metabolic pathways for novel therapeutic strategies in MM.
Main Methods:
- Literature review focusing on metabolomics studies in multiple myeloma.
- Analysis of research on metabolic reprogramming in MM pathology.
Main Results:
- Metabolomics has proven effective in discovering potential biomarkers for MM.
- Targeting specific metabolic pathways shows promise for MM treatment.
Conclusions:
- Metabolomics offers valuable insights into the metabolic mechanisms driving MM.
- Further research can leverage these findings for innovative clinical diagnostic and therapeutic approaches in multiple myeloma.
