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Rethinking fairness in AI to improve current practice in oncology.

Salamata Konate1, Jack Gallifant2, Charles Senteio3

  • 1York University, Toronto, Ontario, Canada; Vector Institute, Toronto, Ontario, Canada.

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|December 3, 2025
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Summary
This summary is machine-generated.

Evaluating artificial intelligence (AI) fairness in oncology is challenging due to biased data and metrics. New fairness frameworks are needed to ensure equitable cancer care for diverse patient populations.

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Area of Science:

  • Oncology
  • Artificial Intelligence
  • Health Equity

Background:

  • Fairness in artificial intelligence (AI) is crucial, especially in oncology.
  • Existing fairness metrics are often flawed and do not account for real-world inequities.
  • Patient diversity and structural biases significantly impact cancer care outcomes.

Purpose of the Study:

  • To highlight the limitations of current fairness metrics in AI for oncology.
  • To emphasize the need for revised fairness frameworks that address biases in data and predictions.
  • To advocate for improved equity in cancer care through better AI evaluation.

Main Methods:

  • Analysis of biases in ground truth labels, AI predictions, and demographic attributes.
  • Critique of standard fairness metrics in the context of oncology.
  • Conceptual framework development for equitable AI in cancer care.

Main Results:

  • Current fairness metrics in AI for oncology are inadequate.
  • Biases are present in datasets, predictions, and demographic data, distorting fairness assessments.
  • A significant gap exists between current AI fairness evaluations and true equity in cancer care.

Conclusions:

  • Rethinking AI fairness frameworks is essential for oncology.
  • Addressing biases in data and metrics is critical for achieving health equity.
  • New approaches are needed to ensure AI promotes equitable cancer care outcomes.