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Evaluating intraoperative C2 slope as a radiographic guide for cervical deformity correction
Namhoo Kim1, Kyung-Soo Suk2, Ji-Won Kwon1
1Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
Scientific Reports
|December 3, 2025
Summary
The C2 slope (C2S) can guide cervical deformity correction surgery. Measuring C2S intraoperatively helps achieve stable alignment and improve patient outcomes.
Area of Science:
- Orthopedic Surgery
- Spine Deformity Correction
- Radiographic Measurement
Background:
- Optimal sagittal alignment is crucial in cervical deformity correction.
- Reliable intraoperative tools for guiding cervical spine alignment are limited.
- C2 slope (C2S) is a parameter reflecting upper thoracic and cervical spine relationship, linked to quality of life.
Purpose of the Study:
- To investigate the role of intraoperative C2 slope (C2S) as a guide for cervical deformity correction.
- To assess the stability of C2S and T1 slope minus cervical lordosis (T1S-CL) after correction.
- To evaluate the correlation between radiographic parameters and clinical outcomes.
Main Methods:
- Analysis of 45 patients with cervical deformity and minimum 2-year follow-up.
- Intraoperative lateral radiographs used to measure C2S for surgical guidance.
- Evaluation of radiographic parameters (C2S, C2-7 lordosis, T1 slope, T1S-CL, sagittal vertical axis) preoperatively, intraoperatively, and postoperatively.
- Assessment of clinical outcomes including pain, disability, and quality of life scores.
Main Results:
- Significant correction and stable maintenance of C2S and T1S-CL were observed postoperatively and during follow-up.
- Final C2S and T1S-CL showed significant correlations with improved clinical outcomes.
- Intraoperative C2S measurement guided surgical adjustments effectively.
Conclusions:
- Intraoperative C2 slope (C2S) is a practical reference for guiding cervical deformity correction.
- Using C2S can lead to favorable radiographic and clinical outcomes in cervical deformity surgery.
- C2S measurement aids in achieving and maintaining optimal sagittal alignment.

