Related Experiment Video
Updated: Jan 9, 2026
Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
Published on: June 13, 2016
How I do it: sequential robot-assisted stereotactic biopsy and laser interstitial thermal therapy for epilepsy
Oumaima Aboubakr1,2, Bertrand Mathon3,4
1Department of Neurosurgery, Sorbonne University, La Pitié-Salpêtrière University Hospital, 47-83, boulevard de l'Hôpital, Cedex 13, 75651, Paris, France.
Background:
Laser Interstitial Thermal Therapy (LITT) is a minimally invasive option for treating epilepsy and neuro-oncologic lesions, including those deemed inoperable. However, it does not allow for histomolecular diagnosis.
Methods:
We describe our technique for combining stereotactic brain biopsy and LITT, focusing on biopsy sample quantity and its effects on MRI thermometry and ablation quality.
Conclusion:
Stereotactic biopsy can be safely integrated with LITT. Limiting sampling to two specimens minimizes air diffusion and hemorrhagic risk, reducing thermometric artifacts and preserving the accuracy of ablation.
