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Updated: Jul 15, 2026

Infant Auditory Processing and Event-related Brain Oscillations
Published on: July 1, 2015
The relationship between auditory steady-state response and behavioural audiometry in hearing estimation for infants:
Xin Huang1, Karolina Kluk1, Emanuele Perugia2
1Manchester Centre for Audiology and Deafness (ManCAD), School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Insights
Auditory Steady-State Response (ASSR) accurately predicts behavioral audiometry (BA) hearing thresholds in infants. Further research is needed due to study heterogeneity, but ASSR is a reliable tool for early hearing loss identification.
Area of Science:
- Audiology
- Pediatric Medicine
- Hearing Science
Background:
- Auditory Steady-State Response (ASSR) is crucial for identifying hearing loss in infants, enabling early intervention.
- Assessing the accuracy of ASSR in determining infant hearing thresholds is vital for effective clinical practice.
- This systematic review evaluates the differences between ASSR and behavioral audiometry (BA) thresholds in infants.
Purpose of the Study:
- To systematically review and quantify the threshold differences between air-conducted ASSR and BA in infants.
- To assess the accuracy of ASSR as a predictor of hearing thresholds in the pediatric population.
Main Methods:
- A systematic literature search was conducted across PubMed, Web of Science, Cochrane, and Embase.
- Infants under 2 years were included, comparing ASSR thresholds to BA thresholds.
- Risk of bias was assessed, and mean threshold differences with 95% confidence intervals were calculated at 0.5, 1, 2, and 4 kHz.
Main Results:
- Seven studies with 2845 thresholds were included in the meta-analysis, indicating moderate quality and high heterogeneity.
- Mean differences between ASSR and BA thresholds ranged from 6.35 dB to 9.24 dB across tested frequencies.
- The results showed ASSR provides a reasonably accurate prediction of BA hearing thresholds in infants.
Conclusions:
- ASSR demonstrates reasonable accuracy in predicting behavioral audiometry thresholds in infants.
- The significant heterogeneity across studies highlights the need for further research.
- Larger infant cohort studies are recommended to refine the accuracy of ASSR for hearing threshold determination.
Background:
Auditory Steady-State Response (ASSR) allows the identification of infants with hearing loss and consequently early intervention. Therefore, it is important to assess the accuracy of ASSR for determining hearing thresholds in infants. This study aimed to systematically review the threshold differences between air-conducted ASSR and behavioural audiometry (BA) in infants.
Methods:
The population was infants younger than 2 years; the intervention was ASSR thresholds; the comparator was BA thresholds; and the outcome was the ASSR-BA threshold, i.e., the correction value in dB. PubMed, Web of Science, The Cochrane Central Register of Controlled Trials, and Embase were searched. The risk of bias was evaluated using the Evidence Project risk of bias tool and the Newcastle-Ottawa Quality Assessment Scale. The mean and 95% confidence intervals (CI) were calculated for the threshold differences at four frequencies (0.5, 1, 2, and 4 kHz).
Results:
Of 503 articles identified, 10 were eligible for a narrative summary, and seven were included in the meta-analysis, which had a total of 2845 ASSR-BA thresholds. The articles were of moderate quality and showed substantial heterogeneity (I2 between 89 and 96%, p < 0.01). The mean differences (± 95% CI) between ASSR thresholds and BA hearing thresholds were 9.24 dB (± 6.45), 7.19 dB (± 4.02), 6.35 dB (± 4.51), and 7.42 dB (± 5.40) at 0.5, 1, 2, and 4 kHz, respectively.
Conclusions:
ASSR provides a reasonably accurate prediction of BA thresholds. Given the heterogeneity of the included studies, further research with larger infant populations is needed.
Systematic Review Registration:
The study was pre-registered in PROSPERO and followed PRISMA-P 2015 statement.
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