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Related Experiment Video

Updated: Jan 9, 2026

Three-Dimensional Reconstruction of Orbital Fractures

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

Star in the Forehead.

Ankur Singh¹, Priyanka Munjal¹, A K Verma¹

¹Department of Pathology, ESIC Hospital and PGIMSR, New Delhi, Basaidarapur, India.

Diagnostic Cytopathology

|December 4, 2025

Summary

Asteroid bodies, rare cell inclusions, were found in a patient

Area of Science:

Cytopathology
Histopathology
Cell Biology

Background:

Asteroid bodies are rare cytoplasmic inclusions within multinucleated giant cells.
They are classically associated with sarcoidosis but can appear in other granulomatous conditions.
Recognition in cytology is challenging.

Purpose of the Study:

To present a case of asteroid bodies in a post-traumatic swelling.
To illustrate the cytomorphological spectrum of asteroid bodies outside sarcoidosis.
To discuss differential diagnoses and clinical relevance.

Main Methods:

Fine needle aspiration cytology (FNAC) was performed on a forehead swelling.
Cytological analysis revealed multinucleated giant cells with asteroid bodies.

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Histopathological correlation was considered.

Main Results:

Numerous foreign body-type giant cells containing asteroid bodies were identified.
The findings were observed in a post-traumatic context, not systemic sarcoidosis.
The case demonstrated asteroid bodies in a less common presentation.

Conclusions:

Asteroid bodies can be found in reactive conditions beyond sarcoidosis.
Accurate cytological identification requires awareness of their varied presentations.
This case broadens the understanding of asteroid body morphology and clinical significance.