Astragalin: A promising herbal compound with broad anticancer potential (Review)

Area of Science:

• Phytochemistry
• Oncology
• Pharmacology

Background:

• Herbal medicines contain compounds investigated for cancer treatment.
• Astragalin exhibits various biological activities, including anti-inflammatory and antioxidant effects.
• Limited literature exists on astragalin's specific anticancer mechanisms.

Purpose of the Study:

• To review and summarize the literature on astragalin's mechanisms of action in cancer.
• To explore astragalin's potential role in cancer prevention and treatment.

Main Methods:

• Literature search and review of studies on astragalin and cancer.
• Analysis of astragalin's effects on cancer cell signaling pathways and molecular targets.

Main Results:

• Astragalin impacts cancer cell proliferation, invasion, and angiogenesis.
• It modulates signaling pathways, apoptotic proteins, oncogenes, and tumor microenvironment.
• Astragalin demonstrates potential in reversing chemotherapy resistance.

Conclusions:

• Astragalin exhibits multifaceted anticancer effects through various molecular mechanisms.
• Its availability, safety, and economic viability suggest a promising future role in cancer therapy.
• Astragalin offers new hope for global cancer treatment strategies.