Changes in gross motor function in children with cerebral palsy following repeated intensive rehabilitation periods:

Viktoria Opheim1, Camilla Skagen2, Kine Melfald Tveten2,3

  • 1Department of Physiotherapy Services for Children and Youth, Interdisciplinary Resource Team, Tromsø, Norway.

Frontiers in Pediatrics
|December 4, 2025
PubMed

Insights

Intensive rehabilitation improves gross motor function in children with cerebral palsy (CP). Repeated therapy periods are most beneficial for young children and enhance function across all GMFCS levels.

Area of Science:

  • Pediatrics
  • Neurology
  • Rehabilitation Medicine

Background:

  • Cerebral palsy (CP) is a group of disorders affecting movement and posture, impacting gross motor function.
  • Intensive rehabilitation is a key intervention for children with CP, but the long-term effects of multiple rehabilitation periods require further investigation.

Purpose of the Study:

  • To evaluate the changes in gross motor function in children with cerebral palsy (CP) after undergoing multiple intensive rehabilitation periods.

Main Methods:

  • A retrospective longitudinal study analyzed 46 children (aged 2-12 years) with CP (GMFCS levels I-V) who underwent 2-12 intensive rehabilitation periods.
  • Gross motor function was assessed using the Gross Motor Function Measure-66 (GMFM-66) and analyzed with linear mixed models.
  • Comparisons were made based on GMFCS levels and age groups.

Main Results:

  • GMFM-66 scores and percentiles significantly increased during intensive rehabilitation periods, particularly the first four.
  • Gross motor function improved across all GMFCS levels, with notable gains in levels I and V.
  • Children under 6 years demonstrated greater improvements compared to older children.

Conclusions:

  • Intensive rehabilitation is associated with improved gross motor function in children with CP, regardless of GMFCS level.
  • Repeated intensive rehabilitation periods show particular benefit in early childhood.
  • Strategic implementation of repeated rehabilitation periods can support long-term functional gains in children with CP.
Abstract

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