Acute Epstein-Barr Virus-Related Myopericarditis in an Immunocompetent Young Adult

Epstein-Barr virus (EBV) is a highly prevalent infection that typically presents as a self-limiting, mild illness. In rare cases, EBV infection can cause life-threatening complications, including myopericarditis. This case report describes a 20-year-old male who developed EBV-associated myopericarditis leading to left ventricular thrombus. This embolized to the gastrointestinal tract, leading to bowel necrosis, septic shock, and admission to a medical intensive care unit. EBV-associated myopericarditis is a rare occurrence, especially for immunocompetent young patients. Thrombus formation in this context is even rarer. This case highlights possible cardiovascular complications of active EBV infection. Clinicians should be aware of the wide array of EBV-associated conditions and maintain suspicion of cardiovascular involvement in the hospital. Patients should be treated at facilities equipped to manage potential cardiovascular involvement if it is suspected.