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Area of Science:

  • Public Health
  • Computer Science
  • Social Sciences

Background:

  • Opioid overdose is a national public health emergency in the US, causing over 500,000 deaths.
  • Identifying patients at risk for opioid use disorder (OUD) requires effective tools for medical practitioners.
  • Social media platforms like Reddit offer insights into sensitive drug-related behaviors through user self-disclosure.

Purpose of the Study:

  • To develop and evaluate models for classifying six phases of opioid use (Medical Use, Misuse, Addiction, Recovery, Relapse, Not Using) from Reddit posts.
  • To investigate the impact of span-level extractive explanations on annotation quality and model performance in OUD phase classification.
  • To assess the effectiveness of state-of-the-art models in supervised, few-shot, and zero-shot learning settings for OUD continuum analysis.

Main Methods:

  • Collected and annotated a corpus of 2500 opioid-related Reddit posts, labeling six distinct phases of opioid use.
  • Annotated span-level extractive explanations for each post to enhance understanding and model training.
  • Evaluated various state-of-the-art machine learning models using supervised, few-shot, and zero-shot learning approaches.

Main Results:

  • Classifying the phases of opioid use disorder is context-dependent and presents significant challenges.
  • The inclusion of explanations during model development led to a substantial increase in classification accuracy.
  • Error analysis highlighted the complexity and contextual nature of identifying OUD phases.

Conclusions:

  • Span-level explanations are beneficial for improving model performance in high-stakes domains like OUD research.
  • Machine learning models, especially when augmented with explanations, show promise for analyzing the opioid use disorder continuum.
  • This approach can aid in developing better tools for identifying at-risk patients and understanding OUD progression.