Related Experiment Video
Updated: Jan 9, 2026
Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
[Literature Review: Acute Pancreatitis]
Sara Pérez-Brotons1, Enrique de-Madaria1
1Servicio de Aparato Digestivo, Hospital General Universitario Dr. Balmis-ISABIAL. Alicante, España. Servicio de Aparato Digestivo Hospital General Universitario Dr. Balmis-ISABIAL Alicante España.
None:
Acute pancreatitis is one of the leading causes of hospital admissions for gastrointestinal disease worldwide. Its incidence has increased in recent years, significantly impacting healthcare costs. It is an acute inflammatory process of the pancreas accompanied by abdominal pain, nausea, and vomiting. The most common causes are gallstones and alcohol abuse, though there are other, less frequent causes. A diagnosis of acute pancreatitis requires the fulfillment of at least two of three criteria: typical abdominal pain, amylase or lipase levels three times higher than the upper limit of normal, and/or compatible imaging findings. The disease can progress from mild forms with rapid resolution to severe cases that can lead to local and systemic complications and multiple organ failure. This condition significantly impacts morbidity and mortality. The latter occurs in 24% of mild cases and up to 50% of severe cases. Since there is no specific treatment for acute pancreatitis, its management is based on supportive measures and addressing the underlying cause to prevent further episodes.
More Related Videos
07:10Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
07:38Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
Related Concept Videos
01:27Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
01:30Acute Pancreatitis II: Clinical Manifestations and Management
01:24Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
01:29Chronic Pancreatitis II: Collaborative Care
Assessment:
01:17Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
01:23Gastritis III: Clinical Manifestations and Management
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...