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Qualitative Factors Impacting Patients and Clinicians Regarding Intravitreal Injections for Retinal Disorders: A
Andrew Ly1, Evan Harnick1, Tanisha Jowsey1
1Faculty of Health Sciences & Medicine, Bond University, Gold Coast, QLD, Australia.
Clinical Ophthalmology (Auckland, N.Z.)
|December 4, 2025
Summary
This review explores patient and clinician experiences with intravitreal injections, crucial for managing retinal diseases. Understanding these perspectives can improve treatment adherence and patient-centered care.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Qualitative Research
Background:
- Intravitreal injections are common worldwide for retinal conditions like AMD, DME, and RVO.
- This review focuses on qualitative research exploring patient and clinician experiences with these injections.
Purpose of the Study:
- To scope qualitative research on patient and clinician beliefs, perspectives, experiences, and behaviors regarding intravitreal injections.
- To identify factors influencing treatment adherence and inform person-centered care models.
Main Methods:
- Searched academic databases (PubMed, Embase, CINAHL, Web of Science) for qualitative studies on intravitreal injections in adults (2000-2024).
- Extracted data on study characteristics, objectives, and methodologies.
- Included 28 studies out of 795 identified citations.
Main Results:
- Patients frequently experience anxiety and uncertainty due to fear of vision loss and the injection process.
- Physical discomfort and pain during injections vary based on clinician technique.
- Clinician decisions are influenced by patient adherence and other personal factors.
- Qualitative research in ophthalmology, often using interviews and thematic analysis, is growing.
Conclusions:
- Qualitative research provides crucial insights into patient and clinician experiences with intravitreal injections.
- Understanding these experiences can lead to more person-centered and sustainable treatment models.
- Addressing qualitative factors can enhance treatment delivery and improve patient adherence.
